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Microfluidic Cell Sorting Chip
MCS-96
Microfluidic single-cell isolation chip for direct isolation into 96-well plates, immediate microscopic verification, and rapid transition from isolation to incubation.
Cell Dispensing System
Direct Single-Cell Isolation into a 96-Well Plate
The Microfluidic Cell Sorting Chip is designed to simplify the front end of single-cell workflows. Isolated cells can be transferred directly into a 96-well plate, reducing the number of handling steps between isolation and culture. This passive isolation chip does not require specialized equipment.
Verify the Isolated Cell Before Incubation
After isolation, researchers can check the well by microscopy to confirm the presence of a single cell. This immediate verification helps establish a clear starting point before the plate is moved into incubation.
A Faster Alternative to Prolonged Limiting-Dilution Workflows
Traditional limiting-dilution methods can require repeated dilution, plating, observation, and regrowth over an extended period. The chip is intended to shorten this process by enabling direct cell isolation and immediate progression to culture, helping researchers reduce dependence on workflows that may otherwise take several weeks.
FEATURES
- • Direct single-cell isolation into standard 96-well plates.
- • Compact microchannel design with unique flow paths.
- • Immediate microscopic verification of the isolated cell after isolation.
- Enables cell isolation based on size.
- Reduces the number of manual handling steps between isolation and culture.
- Designed to help shorten workflows that otherwise rely on time-consuming limiting dilution.
- Microfluidic approach supports compact, workflow-oriented cell handling.
APPLICATION
Cell Therapy and Advanced Cell Research
Supports standardized preparation of multiwell plates for cell therapy development and other cell-based research where consistent cell distribution is important.
Biopharmaceutical R&D and Cell-Based Assays
Useful for plate-based experiments that require repeatable cell seeding before screening, culture, treatment, imaging, or other downstream analysis.
CDMO and Multi-Project Laboratory Workflows
Automation can reduce repetitive manual work and improve consistency across operators, making the system attractive for development laboratories and CDMO environments handling multiple cell-based projects.
Precious or Limited Cell Samples
The low-residue fluid path is particularly relevant when only a small amount of cell suspension is available or when sample conservation is a priority.
SPECIFICATION
| Item | Specification |
|---|---|
| Dimension | 300 x 300 x 300 (mm) |
| Work area | 10 x 150 (mm) |
| Input voltage | DC 12V / 2A |
| Compatibility | 6 / 12 / 24 / 48 / 96-well plates |
| Power adapter | AC 100~200V |
| Material | Aluminum / Stainless steel / Acrylic / Plastic |
| Operation method | Touch control interface / button |
| Vibration freq. (cpm) | 0~90 |
| Swing angle (degree) | 0~90 |
| Droplet size | Adjustable based on requirements |
| Consumables | Sterilized dedicated tubes (PP material) and rear-end tubing components |
DIRECTION FOR USE
A typical research workflow is outlined below. Exact settings should be established for the cell type, concentration, medium, and study protocol.
- Prepare a well-dispersed cell suspension according to the laboratory protocol and confirm that the suspension is suitable for dispensing.
- Select the required 24- or 96-well plate format and place the plate in the designated dispensing position.
- Load the cell suspension and install the appropriate fluid path or dispensing accessories according to the system setup.
- Set the dispensing parameters required for the experiment.
- Start the automated dispensing cycle and allow the system to complete plate filling.
- Inspect the plate and cell distribution as required by the study protocol before proceeding to culture or downstream analysis.
- After use, follow the laboratory-approved cleaning, decontamination, or consumable-replacement procedure.
Note: Cell viability and dispensing performance can vary with cell size, concentration, aggregation tendency, medium viscosity, and selected operating parameters.
FAQ
| 1. What plate formats can the Automatic Cell Microplate Dispenser handle? The system is designed for automated cell dispensing into 24-well and 96-well plates. |
| 2. Why is low residual volume important for cell dispensing? Low residual volume means less cell suspension remains in the fluid path after dispensing. This helps conserve precious or small-volume samples and can reduce unnecessary sample loss. |
| 3. How does the system improve reproducibility compared with manual pipetting? Automation standardizes the dispensing step and reduces variation caused by repetitive manual operation. This can improve well-to-well consistency and operator-to-operator reproducibility. |
| 4. Is the dispensing process suitable for sensitive cells? The system is designed for gentle, cell-friendly dispensing that minimizes unnecessary mechanical stress. Actual cell recovery and viability should still be verified for each cell type and protocol. |
| 5. Who is the system intended for? It is particularly relevant to cell therapy developers, biopharmaceutical R&D teams, CDMOs, and research laboratories that routinely prepare multiwell plates with cell suspensions. |
| 6. Can the same settings be used for every cell type? Not necessarily. Cell size, concentration, aggregation tendency, medium composition, and viscosity can affect dispensing behavior. Parameters should be optimized and verified for each application. |
| 7. Is this system intended for clinical diagnosis? It positions the system for cell research and development workflows. Any clinical or diagnostic use would require separate confirmation of the applicable regulatory status. |
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