【Skin Care】Hexamethyldisiloxane (HMDS) Skin Protection Technology: The Key to Preventing Diaper Rash | OEM/ODM & Private-Label Healthcare Supply for Hospitals & Retail - Hannox

【Skin Care】Hexamethyldisiloxane (HMDS) Skin Protection Technology: The Key to Preventing Diaper Rash | Medical and Home-Care OEM/ODM – Private-Label Sourcing - Hannox

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【Skin Care】Hexamethyldisiloxane (HMDS) Skin Protection Technology: The Key to Preventing Diaper Rash | Medical & Home-Care OEM/ODM Supplier – Private Label - Hannox

Hannox International Corp. is a medical device OEM/ODM and global sourcing partner for blood glucose meters and strips, wound-care dressings, natural mosquito repellents, dental units, and home-care devices. We help hospitals, clinics, distributors, and retailers launch accurate, safe, easy-to-use products.

We manage end-to-end private-label projects—selection, customization, branding and packaging, labeling/IFU, QA/QC, and compliance documentation (ISO/CE where applicable)—through a vetted network of partner factories. Expect clear MOQs, predictable lead times, and consistent quality across diabetes care, wound care, dental, and home-care categories.

Hannox delivers high-quality home-care and patient-monitoring devices, backed by advanced technology and 22 years of expertise. We support OEM/ODM and private-label sourcing—selection, customization, packaging, and compliance—so professional buyers launch standards-ready products fast.

【Skin Care】Hexamethyldisiloxane (HMDS) Skin Protection Technology: The Key to Preventing Diaper Rash

Diaper rash is one of the most common skin problems in infants and young children. It's primarily caused by irritants in urine and feces, combined with humidity, heat, and friction, which can easily cause redness, rashes, and even breakouts on a baby's delicate skin. While traditional care methods can alleviate symptoms, in recent years, the medical community has increasingly focused on skin barrier technology, with hexamethyldisiloxane (HMDS) becoming a focus of research and clinical attention.

liquid bandage

Why do urine and feces trigger diaper rash?

  • Ammonia in urine: Enzymes in urine raise the skin's surface pH, damaging the stratum corneum.
  • Enzymes in feces (lipases and proteases): Directly damage the skin barrier.
  • Heat and humidity, combined with friction, increase skin damage, leading to erythema, erosions, and even secondary infections. Therefore, establishing an effective protective barrier to block urine and feces from entering the skin is crucial for diaper rash prevention.

How HMDS Works

HMDS is a volatile silicone commonly used in medical-grade skin barrier products (such as 3M™ Cavilon™ Advanced Skin Protectant；Hannox™ Sting Free Barrier Film). Its characteristics include : rapid evaporation to form a protective film; close adhesion to the skin, resistance to friction, and resistance to shedding; breathability without being stuffy; and long-lasting protection lasting for hours to days. These properties make HMDS an ideal urine and feces barrier, demonstrating excellent protection against incontinence-associated dermatitis (IAD) and infant diaper rash.

Clinical and Research Evidence

Incontinence-associated dermatitis (IAD) and barrier care: A systematic review by Beeckman et al. (2015) showed that the use of skin barrier products containing HMDS significantly reduced the severity of dermatitis and the incidence of urine- and feces-related skin lesions. Infant Diaper Rash Care Study: Atherton, 2016. A study on infant skin care found that consistent use of barrier products can reduce the frequency of diaper rash episodes and effectively protect the skin from urine and feces irritation.

Hexamethyldisiloxane (HMDS) has been shown to effectively form a durable skin barrier and has significant clinical value in preventing and alleviating diaper rash. It creates a barrier between a baby's delicate skin and urine and feces irritation, reducing the frequency of rash episodes, improving care efficiency, and enhancing baby comfort.

IAD

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